Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

清华大学位列第45名,是亚洲排名第三的高校。北京大学位居第57位。浙江大学排名第67位,本次是该校首次跻身该榜单100强。
这块白板经常被写满公式。但你是否曾好奇过这些公式都有什么含义?我们也许没有机会知道它们代表什么,但它们的确都是真实准确的公式。这一点相当给力。
Additional reporting from Stefan Wagstyl in Berlin
合肥市和厦门市分别以48.6%和45.9%的涨幅再次领涨。
但是,这一情况在两年前发生了变化,清华大学首次跻身前20名,2016年排名第18位。去年,北京大学也跻身前20名。
The requirements come from one of two newly issued regulations over the taxi and online ride-hailing services by China's transportation authority. The regulations will take effect in October and November respectively.
网队重建的欲望已经超越了给波士顿另一个高顺位签的不情愿。大坑已经挖好,想要从坑里爬出来,你能做的只有:一步一步地,挑出合适的新秀,交易球员,以及签约。
"There was a large crowd outside, including my teachers and other parents, people looked quite agitated," Sun said of the moment he was rescued.
Gymnastics;Trampoline;Artistic gymnastics;Rhythmic gymnastics
35岁的阿德里亚娜·利马身着一件凸显身材的白色抹胸式礼服。这位巴西模特选择了简单又时髦的装扮,她把头发扎了起来,戴着一条抢眼的项链,项链上缀满了钻石。
项目长度:22个月
Choose the number next to each statement that best reflects your feelings.
“我们做事情不是为了追求利润,我们做事情,是因为这些事情是正确和公正的,”库克咆哮道。他说,不管是为了人权、可再生能源还是为有特殊需求的人们提供帮助,“我不考虑该死的投资回报率”。“直截了当地跟你说,如果这是你考虑的硬性因素……那你还是把苹果股票卖了吧。”库克的语气严厉,毫不妥协,那是苹果员工或许永远不希望面对的一个声音。
We will continue to work to see that government functions are fully carried out in accordance with law.
Singer Susan Boyle came undone -- literally, when her trousers popped open at a soccer match as she waved a Celtic fan above her head in Scotland. The "Britain
达福目前可能是最佳男配角的领跑者。
If successful, the funding would underline the rapid growth of the sector this year. In April, Lufax raised $500m at a $10bn valuation.
Writing for a Variety Special: Patton Oswalt, “Patton Oswalt: Talking for Clapping”
What’s more, a Fiat engine not only places among Wards’ top 10 for the first time, it’s for an electric motor, the 83-kW unit found under the hood of the diminutive 500e. Unfortunately the car is only sold in California, though market forces might convince the automaker to send it into wider distribution should gas prices gain spike up to the $4.00/gallon mark or above.
阅读成功的商业案例。吸收史蒂夫o乔布斯等成功创业者以及《创智赢家》(Shark Tank)提供的知识财富。一份成功的商业计划书不需要长篇累牍。10页纸的商业计划书既便于理解,又足以包含你要开始实施的所有内容。
3.你老板从他认识的人那收到了你认识的人给的简历。
romantic
沿海江苏省的无锡市以4.9%的环比涨幅连续第二个月处于首位。
On April 24, Zhou took the pesticide to the Yimin Technician Training School in Rongchang, Chongqing and hid the toxic substance under a desk.
以下是2012年搞笑诺贝尔奖得奖名单,这些奖项被授予那些做出看起来愚蠢却又对世界有深度贡献的科学家、作家、和平缔造者们,或者用主办方《不可思议研究年报》的话来说就是奖励那些“乍看起来让人发笑,但是随后发人深省”的研究工作。我敢担保,这些发明绝对能使人们大笑!


In interviews, everyone works well with others, and everyone learns quickly. Please tell me something else.
This is a story about six friends with precarious love lives who spend their days sitting in a cafe sipping coffee from oversized mugs. Who’d have thought this premise would go on to become one of the most influential sitcoms of all time?
今年,全球2000强企业来自62个国家,比起2003的首届排行榜的46个国家数量上升了。这些企业总共创造了38万亿美元的营收及3万亿美元的利润,总资产达161万亿美元,总市值则达到44万亿美元。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

“This is our make or break moment for the tenant movement,” said Ilana Maier, the program director for the Metropolitan Council on Housing. “If we aren’t able to drastically strengthen the rules now, none of this will matter in 10 years.”
该读数最后一次高于50是在2月份。对于该指数来说,是否高于50是区分制造业活动是扩张还是收缩的荣枯线。
For: The Los Angeles Critics Association gave it their top prize.
酒店和餐饮业高管薪酬均值增速最快,均为47.58%。

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

西安咸阳国际机场的准点率为82.3%,在国内所有机场中位居第一。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

农村贫困人口减少1240万;
ESCP欧洲商学院(ESCP Europe)和美国麻省理工学院斯隆管理学院(MIT Sloan School of Management)也表现不错。两所学院的排名均上升5位,分别位居第三和第五。

周二在华盛顿DC倒下的大树把一条街拦住了。
On Tuesday Saarland became the first German region to ban campaigning by foreign politicians. Several German local councils had called off planned Turkish ministers’ campaign meetings on technical grounds, such as fire safety.
Though bionic legs are of course a huge boon to amputees, they lack actual nerve connections with the body. As a result, walking on them is cumbersome and tiring. But last year, Seattle resident Zac Vawter was outfitted with the world's first thought-controlled leg, a bionic limb that takes signals directly from his mind.
这是英国影评人参与评选的娱乐性奖项,为在参展影片中表现最精彩的狗颁发纪念奖章。颁奖仪式于上周五(5月22日)在英国展馆举行。今年的金棕榈狗狗奖颁给了一只名叫幸运的狗,它是马耳他梗犬(Maltese terrier)与贵宾犬(Poodle)的混血品种。幸运出现在米古尔?戈麦斯(Miguel Gomes)时长6小时的巨作《一千零一夜》(Arabian Nights)中,在剧中叫做迪克西。幸运的奖品是一只玩具狗骨头,通过视频幸运发表了简短的获奖感言(汪)。但据法新社报道,在这大家其乐融融的时刻,一位法国记者认为在极具魅力的影展间隙举办这样的颁奖仪式真是“英国人愚蠢性格的无端干扰”。“在法国人看来,这有些奇怪,”他在报道中说。“英国人真是不可思议。”
Hua Xu Yin is about a princess who sacrificed her life for the country but later was saved and began her own adventures with another name. It is also a TV series adaptation of an online novel of the same title written by Tang Qi. The series premiered in July 2015, staring Lin Yuan and Zheng Jiaying. However, it did not get as much attention as its rivals. According to the online critics, the lead roles and their costumes were not appealing enough in the adaptation.
澳大利亚整体排名第八,这个位于南半球的国家,“生活质量”排名第四,“冒险指数”排名第九,教育排名第十。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


业主们 这些隐形收益你们知道吗


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


For now, D'Aloisio isn't touching the money. 'I'm too young to appreciate the value of it,' he insists. 'I don't have a mortgage, I'm 17. To me, a hundred pounds is a lot. Take that as a benchmark.' Though he's not allowed to comment on Summly's sale price, when pressed he allows that he might one day like to deploy his newfound riches as an angel investor. No one around him seems to think there's a danger that the money will ruin him or that he'll be tempted to spend the rest of his life dissipating on a beach. 'He's pretty well grounded. You wouldn't believe how frugal he is,' says Diane. 'He's got a great engine,' says Lou. 'He won't stop at this.'
企业客户看重该校的灵活性和创新能力。“我们开发的一个课程,是由一个试验性学习提供者共同教授的,”一名收到英国《金融时报》调查问卷的该校客户反馈道,“Iese在这一过程中一直是一个真正的合作伙伴,而我们的企业也获益于一支充满活力且准备充分的高管后备军。”
雅虎首席执行官玛丽莎梅耶尔
民粹主义的兴起(即使在美国和英国这样的就业人数众多的国家也是如此)使得政客们认识到,就业的质量和数量同等重要。
然而,在开始攻读EMBA课程之前,男女学员之间已然存在巨大的薪资差距,女性平均薪资较男性低15%,女性和男性的这个数字分别为11.1万美元和12.8万美元。
People were busy launching businesses or making innovations.
大病
荷兰合作银行是面向全球农户和农业企业的领先融资机构。
单词embrace 联想记忆:
Best Luxury Brand: Porsche

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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Whatever one's view, two further points for and against Russia's global standing are undeniable:
But there's even more to be excited about: Magic Johnson is a well-connected and well-respected Hall of Famer who seems smart enough to delegate, new GM Rob Pelinka is a proven deal-maker with extensive ties throughout the league,
雷文斯克罗夫特认为,如果他成为一名管理顾问,他的视野可能会相对狭窄。教学工作也有助于他变得愿意承担风险——这来之不易。“如果你曾站在30名会毫不犹豫地指出你的错误的青少年面前讲课,这种体验可能会让你变得愿意去尝试。”
Dafoe is probably the current front runner for best supporting actor.

In a humiliating 111-77 loss to the Golden State Warriors at Oracle Arena, Bryant shot 1-of-14 from the field, including 1-of-7 from 3-point range, and scored four points. He also shot 1-of-14 in a loss last season to the San Antonio Spurs.

  • Only the first three authors are listed, followed by "et al."
  • 品牌房企云集亦庄区域 品质竞争日渐加剧
  • 北京五环内唯一共有产权房启动“拼装”


体育在热门趋势搜索排行中占据了优势地位,对2012欧洲杯和奥运门票感兴趣的人最多,排名超过了休斯顿和凯特王妃。
Plenty of dark clouds loom over the U.S. job market -- particularly the potential double-punch of tax increases and spending cuts known as the fiscal cliff.[qh]

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